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TheraProteins Galα1-3Gal motif on N-linked oligosaccharides
Galα1-3Gal motif containing structures
 Some recombinant glycoproteins (e.g. from CHO cells) contain small amounts of undesired glycan structures with the Galα1-3Galß1-4GlcNAc–motif which are assumed to be antigenic in humansTheraProteins provides appropriate reference oligosaccharides for detection of these glycans at early stages of biotech process set-up with mammalian expression systems and to quantitate them during downstream processing steps and in the final drug substance.
Asialo diantennary plus 1 α1→3Gal plus proximal α1→ 6 Fucose
Asialo diantennary plus 1 α1→3Gal
Asialo diantennary plus 2 α1→3Gal plus proximal α1→ 6 Fucose
Asialo diantennary plus 2 α1→3Gal
Monosialylated (2-6 linked) diantennary plus 1 α1→3Gal plus proximal α1→ 6 Fucose
Monosialylated (2-6 linked) diantennary monogalacto plus 1 α1→3Gal